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Women's and Men's Health

6 Signs of Perimenopause You Shouldn’t Ignore (And What to Do)

Healthline Mantra Editorial Team
By Healthline Mantra Editorial Team
Last updated: December 7, 2025
11 Min Read
Signs of perimenopause
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You’re 38, maybe 42. And lately, you feel… different.

Contents
Perimenopause vs. Menopause: What’s the Difference?6 Common Signs of Perimenopause to Watch For1. Intense Mood Swings (The “Rage”)2. Sleep Disruption (The 3 AM Wake-Up)3. Brain Fog and Memory Lapses4. Irregular Periods and Cycle Changes5. Unexplained Weight Gain (The Belly Shift)6. Heart PalpitationsPractical Solutions for Perimenopause ReliefTrack Your CyclePrioritize Strength TrainingStabilize Blood SugarConsider Hormone Replacement Therapy (HRT)The Bottom Line: Trust Your BodyFAQsWhat are the very first signs of perimenopause?At what age does perimenopause start?Does perimenopause cause weight gain?What is the difference between perimenopause and menopause?

Not sick, exactly. Just “off.”

Maybe you’ve started waking up at 3:00 AM, heart pounding, for absolutely no reason. Maybe your patience, which used to be made of steel, now snaps over the tiniest things—like a dishwasher loaded “wrong” or a red light that takes too long.

Or perhaps you are dealing with irregular periods—cycles that show up three days early, ten days late, or not at all.

You might tell yourself you’re just tired. You’re stressed. You’re juggling work, family, and a million other things. And while that’s probably true, there might be a biological engine driving these changes.

Welcome to the world of early perimenopause.

It’s a word that often gets whispered, like it’s a scary secret. But it isn’t. It’s a completely normal, natural transition. However, because the average perimenopause age can start surprisingly early, many women miss the clues.

Here is the hard data on the signs of perimenopause, how to spot them, and the proof that you aren’t losing your mind—you’re just shifting gears.

Perimenopause vs. Menopause: What’s the Difference?

First, let’s clear up the confusion between perimenopause vs menopause.

Think of menopause as a destination: the day you haven’t had a period for 12 months in a row. Perimenopause is the road trip to get there.

According to Johns Hopkins Medicine, this trip typically starts between ages 40 and 45. But for about 10% of women, the signs start popping up as early as the mid-30s.

It’s also important to know this isn’t a quick weekend getaway. The median length of perimenopause is about 4 years, though for some, it can last up to a decade. During this time, your ovaries start producing erratic amounts of estrogen and progesterone.

Instead of a steady beat, your hormones play a chaotic jazz solo. Those fluctuations are exactly why you feel like a stranger in your own body.

6 Common Signs of Perimenopause to Watch For

When we think of this transition, we think of hot flashes. But those are often the last symptom to show up. The earlier signs of perimenopause are subtler, sneakier, and easy to miss.

Here are six things to watch for in your late 30s and 40s.

1. Intense Mood Swings (The “Rage”)

We aren’t talking about having a bad day. We are talking about a sudden, intense rage or tearfulness that feels totally out of proportion. If you feel this, you’re in good company: mood swings affect around 60% of us during this time.

The Reality: Estrogen helps regulate serotonin (the happy chemical) and cortisol (the stress hormone). When estrogen drops, serotonin dips and cortisol spikes.
What it feels like: Crying during a car insurance commercial or feeling a sudden urge to scream because someone is chewing too loudly.

2. Sleep Disruption (The 3 AM Wake-Up)

You fall asleep fine, but a few hours later, ping! You are wide awake. Sleep disturbances are incredibly common, hitting up to 50% of women during this transition.

The Reality: Progesterone is nature’s sedative; it helps you stay asleep. During perimenopause, progesterone levels fall faster than estrogen levels. Without that natural calming hormone, your sleep gets fragmented.
What it feels like: Staring at the ceiling for hours, doing mental math about how much sleep you’ll get if you fall back asleep right now.

3. Brain Fog and Memory Lapses

You forget names of people you know well. You lose your keys three times a day. You struggle to find the right word in a meeting. This affects about 30–40% of women.

The Reality: Estrogen is crucial for cognitive function. It protects the neurons in your brain. When levels fluctuate, you can experience temporary lapses in memory.
What it feels like: Your brain is full of cotton wool. It can be scary—many women worry they have early dementia—but usually, it’s just one of the common signs of perimenopause.

4. Irregular Periods and Cycle Changes

Cycle changes are occurring in over 80% of women in this stage. Your cycle might shorten to 24 days, then lengthen to 35.

The Reality: This is the hallmark of the transition. Your ovulation is becoming hit-or-miss, which throws off the timing of your bleed.
What it feels like: You feel like a teenager again, terrified of leaking, carrying emergency supplies everywhere you go “just in case.”

5. Unexplained Weight Gain (The Belly Shift)

You’re eating the same food. You’re doing the same workouts. But suddenly, your jeans won’t zip. Research shows that after menopause, women typically gain 36–49% more visceral fat (the deep belly fat).

The Reality: As estrogen drops, your body shifts fat storage from your hips and thighs to your belly. This perimenopause weight gain isn’t just cosmetic; this type of fat is linked to a doubled cardiovascular risk.
What it feels like: You feel bloated and “thick” around the middle, and your usual diet tricks stop working.

6. Heart Palpitations

This is one of the scariest symptoms. About 20–30% of women report heart palpitations—a flip-flop feeling or a racing heart while sitting still.

The Reality: Estrogen receptors are actually present in your heart muscle. Fluctuating levels can trigger minor flutters.
What it feels like: Anxiety, but it happens even when you aren’t anxious. (Note: Always get heart symptoms checked by a doctor to rule out other issues).

Practical Solutions for Perimenopause Relief

First, take a deep breath. Knowing why this is happening is half the battle. You aren’t failing at life; you are navigating a physiological storm.

The NHS and menopause specialists recommend a mix of natural perimenopause relief and medical support. And the data shows these strategies actually work.

Track Your Cycle

Before you go to the doctor, keep a log for three months. Track your periods, your mood, and your sleep.

  • Why: Doctors often dismiss these signs of perimenopause as “just stress.” Showing a cyclic pattern helps them see the hormonal link immediately.

Prioritize Strength Training

If you rarely exercise, now is the time to start. Women who strength train and do moderate cardio report 30–50% fewer menopausal symptoms.

  • The Shift: Lift heavy things to protect your bones and fight that belly fat. Mix in yoga to lower stress hormones.

Stabilize Blood Sugar

To fight the blood sugar crashes that make mood swings worse, focus on stability.

  • The Shift: Start your day with a high-protein savory breakfast (like eggs or Greek yogurt) instead of sweet carbs.

Consider Hormone Replacement Therapy (HRT)

For a long time, HRT had a bad reputation. But today, experts (including the North American Menopause Society) agree: for most healthy women under 60, Hormone Replacement Therapy benefits usually outweigh the risks.

The numbers are staggering:

  • Hot Flashes: Modern HRT reduces them by 75–90%.
  • Sleep: It improves sleep quality by 40–60%.
  • Mood: It helps stabilize that “murderous” rage.

The Bottom Line: Trust Your Body

Perimenopause is a transition, not an ending.

For years, you may have pushed through fatigue, ignored your needs, and put everyone else first. Recognizing the signs of perimenopause forces you to slow down, to rest, and to finally pay attention to you.

If you recognize yourself in this list, don’t suffer in silence. Talk to your friends. Make an appointment with a doctor who specializes in midlife health.

This isn’t the end of your vitality. With the right support, it’s just the beginning of a new—and honestly, more powerful—chapter.


FAQs

What are the very first signs of perimenopause?

The earliest signs of perimenopause often include irregular periods (cycles becoming shorter, longer, or heavier), intensifying mood swings or “rage,” and sleep disturbances like waking up at 3 AM. While hot flashes are the most known symptom, subtle changes like brain fog, heart palpitations, and increased anxiety often appear first.

At what age does perimenopause start?

Perimenopause typically begins between ages 40 and 45. However, approximately 10% of women may experience symptoms as early as their mid-30s. This transitional phase lasts an average of four years but can extend up to a decade before a woman reaches menopause (12 months without a period).

Does perimenopause cause weight gain?

Yes. As estrogen levels decline, the body tends to shift fat storage from the hips and thighs to the abdomen (visceral fat). Research shows post-menopausal women typically have 36–49% more belly fat than pre-menopausal women. This is often due to hormonal fluctuations combined with a natural slowing of metabolism.

What is the difference between perimenopause and menopause?

Menopause is a specific point in time defined as having gone 12 consecutive months without a menstrual period. Perimenopause is the transitional “road trip” leading up to that day, characterized by fluctuating hormones, irregular cycles, and active symptoms like hot flashes and mood changes.

Disclaimer: This blog post is for informational purposes only and does not constitute medical advice. Always consult with a healthcare professional regarding any symptoms or treatment options.

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